On August 27, 2024, the U.S. Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) announced the deregulation of one genetically modified wheat, one genetically modified sweet orange and one genetically modified grapefruit. Among them, the genetically modified wheat IND-00412-7 was developed by Trigall Genetics SA, a joint venture between Argentina and France, through the transfer of HahHB4 gene and bar/PAT gene, both drought tolerance and resistance to phosphate. Genetically modified sweet orange and genetically modified grapefruit were developed by the University of Florida, the United States, through the transfer of NPR1 gene and NPTII gene, both resistant to citrus greening, kanamycin and neomycin characteristics.

In the end, APHIS concluded through a risk assessment that none of these GM plants is likely to pose a higher risk of plant pests and diseases than their unregulated counterparts. So APHIS deregulated it.