On October 29, 2024, the Animal and Plant Health Inspection Service (APH IS) of the U.S. Department of Agriculture (USDA) announced the deregulation of one gene-edited almond, one genetically modified tomato, and one genetically modified corn. The gene-edited almonds were developed by Ohalo Genetics in the United States to improve self-incompatibility by reducing or losing the self-incompatibility function of the pistil and pollen; the transgenic tomato was developed by Norfolk Plant Sciences in the United States to increase the content of polyphenol compounds in tomato fruits through the expression of the Myb12 transcription factor; and the transgenic corn was developed by the United States The transgenic maize was developed by Greenlab in the U.S. by expressing endoglucanase and bar/PAT genes, which combines increased endoglucanase content and glufosinate tolerance.

APHIS concluded through its risk assessment that none of the above gene-edited/transgenic plants were likely to pose a higher risk of plant pests and diseases than their non-regulated counterparts. As a result, APHIS deregulated them, but they remain subject to EPA and FDA regulation.